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Nancy has over two decades experience at the mic. In addition to her work on The Simpsons, she has lent her voice to characters on various other animated series, including Kim Possible, The Replacements, Richie Rich, Animaniacs, Pinky and the Brain, My Little Pony, The Critic, God, The Devil and Bob, Mike, Lu & Og, Pound Puppies, The Snorks, Galaxy High as well as Chuck Jones' final work, Timberwolf.

Cartwright has also appeared on camera in numerous television series and movies, playing roles in Fame, Empty Nest, Cheers, The Fresh Prince of Bel-Air, Twilight Zone: The Movie, Flesh + Blood, and Godzilla as well as the lead in the TV movie Marian Rose White. Cartwright also appeared in a Season 6 episode of 24 as Jeannie Tyler, the woman Chloe O'Brian thinks is Morris O'Brian's current AA sponsor (filmed during the same season, Kiefer Sutherland and Mary Lynn Rajskub reprised their roles as Jack Bauer and Chloe O'Brian on the Simpsons episode "24 Minutes").

Cartwright is also the voice of Putt-Putt in the Putt-Putt computer game Putt-Putt Enters The Race. She was invited to perform the female voices for South Park, but declined, claiming the show was too offensive even for her standards. The role then went to Mary Kay Bergman.

Her best-selling autobiography, My Life as a Ten-Year-Old Boy (Hyperion/Bloomsbury, 2001), offers a behind-the-scenes look at the phenomenon of The Simpsons. This book was converted into a stage show, which was performed at the Edinburgh Festival Fringe in 2004. She recorded an updated version of the autobiography, which was released as an audio book in 2004. (wikipedia.org)